Unlocking insights: simplifying single-cell data with Strand’s scRNA portal

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Simplifying single-cell data exploration with Strand’s scRNA portal

In the rapidly advancing world of single-cell RNA sequencing (scRNA-seq), navigating complex datasets can be a major challenge. Strand’s scRNA Portal is designed to transform this challenge into an opportunity by harmonizing publicly available datasets, making disease-specific omics data accessible, actionable, and ready for discovery.

Why strand’s scRNA portal was built

1) Focus on unmet needs in key diseases

Starting with datasets with diseases with significant unmet clinical need:

Inflammatory bowel disease: Covering Ulcerative Colitis and Crohn’s Disease.

Neurodegenerative disorders: Including Alzheimer’s Disease, Parkinson’s Disease and Frontotemporal Dementia.

2) The rise of scRNA-seq in aiding precision medicine: Single-cell RNA sequencing provides unprecedented insights into cellular heterogeneity, which is pivotal for identifying biomarkers, validating drug targets, and advancing precision medicine.

Market potential: IBD and neurodegenerative diseases are emerging therapeutic markets with high-impact opportunities for data-driven breakthroughs.

Key features of Strand’s scRNA portal

🔹 19+ million cells, 2400+ samples and 150+ datasets across 5 diseases.

🔹 Metadata standardization: 80+ metadata fields, with a subset being mapped to defined ontologies for consistency and usability.

🔹 Interactive visualization: Explore the data showcase with 23 metrics displayed as bar graphs, pie charts, and line charts—all exportable to suit your requirements.

🔹 Advanced filters: Use 26 filters or a search bar for quick, targeted access to datasets of your choice.

🔹 Curation requests: Request customized dataset curation through the ‘Curation Request’ page to meet your research needs.

Strand's scRNA portal can help you with applications suited to your needs, including biomarker discovery, patient stratification, drug repurposing, machine learning (ML) applications, etc.

What’s next?

Strand team is working on meta-analyses of curated datasets to extract valuable insights and building AI tools to facilitate downstream analysis. Stay tuned for updates!

Take the first step:

Visit the portal and explore how we’re transforming single-cell data exploration.

Additional information: https://scrna-curation.mystrand.org/

Location: Oxford, UK

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